CBSE Class 12 Biology Sample Paper 2027 with Solutions PDF (2026-27)

Download the CBSE Class 12 Biology Sample Paper 2027 PDF with its marking scheme (solutions) – the official CBSE sample question paper (SQP) for the 2026-27 session, the paper to practise for the CBSE Class 12 board exam 2027. It is a 70-mark, 3-hour paper with 33 questions in 5 sections. The pattern is the same as the 2026 sample paper. The 2026 and 2025 sample papers are also here. Students also call it the CBSE 12th Biology model question paper 2027 or model test paper – it is the same official CBSE paper.

CBSE Class 12 Biology Sample Paper 2027 PDF Download

Open a paper to read it online or download the PDF. The marking scheme has the answers, with the marks for each step.

CBSE 12th Biology Model Question Paper 2027 – Quick Facts

CBSE Class 12 Biology Sample Paper 2027 – Read Online

CBSE Class 12 Sample Paper 2027 for Biology Open PDF

CBSE Class 12 Biology Paper Pattern 2027

How the 2027 sample paper is set (from the paper itself) – 70 marks, 3 hours, 33 questions:

Choice: No overall choice; either/or choice in Q17, Q20 and Q21 (Section B), in the last 1-mark sub-part (C or D) of both case-based questions Q29 and Q30, and in all three Section E questions (Q31–Q33); none in Sections A and C.

• All 33 questions are compulsory.
• Wherever necessary, neat and properly labelled diagrams should be drawn.
• For Q1–12, select and write the correct choice as well as the answer.
• Alternative questions are given for visually impaired students in place of figure-based Q4, Q5, Q6, Q8 and Q23.

Unit-wise Marks in the Biology Sample Paper 2027

Marks for each unit (counted question by question from the 2027 paper):

What Is New in the Biology Sample Paper 2027?

Compared with the 2026 sample paper (session 2025-26):

• No change in pattern – same 33 questions, 70 marks, 3 hours, identical General Instructions and Sections A–E with 16/10/21/8/15 marks (12 MCQ + 4 Assertion-Reason, 5×2, 7×3, 2 case-based ×4, 3×5) as the 2025-26 sample paper.
• Internal choice is in the same places as 2025-26 (Q17, Q20, Q21; sub-part C/D of Q29 and Q30; Q31–Q33).
• Visually-impaired alternatives moved mostly into Section A: 2026-27 gives them for Q4, Q5, Q6, Q8 and Q23; 2025-26 gave them for Q21, Q23, Q24, Q28, Q30 and Q31.
• More data/scenario-based questions: hypothetical data tables in Q19 (tumour size vs glucose, oxygen and neighbouring-cell viability), Q20A (α-lactalbumin in Rosie’s milk) and Q21 (seasonal temperatures with GPP/respiration, or pollinator seed-set), and clinical/field scenarios in Q22 (ART for a couple), Q29 (irregular menstrual cycle) and Q30 (NPV against cabbage looper).
• Footer note changed from ‘assessment scheme of the Academic Session 2024-25 will continue in … 2025-26’ to ‘There is no change in the Question Paper Design and Assessment Pattern for Academic Session 2026-27’.
• Paper length: 12 pages in 2026-27 vs 11 pages in 2025-26.

Questions from the Biology Sample Paper 2027

Two questions from the 2027 paper, to show the level:

• Section A, 1 mark: A male patient undergoes a procedure where a small section of the vas deferens is cut and tied at both ends. Which is the intended and direct result? (A) Blockage of sperm transport into the ejaculatory duct and urethra (B) Inhibition of testosterone production (C) Suppression of seminal plasma formation (D) Prevention of spermatogenesis
• Section D, 4 marks: Case (Q30): A tribal farmer growing cabbage in a forest rich in pollinators and rare butterflies applies Nucleopolyhedrovirus (NPV) against cabbage looper caterpillars; the pest declines without affecting other insects. A. Justify why NPV was a suitable choice (1). B. Suggest another IPM strategy for caterpillar pests and describe its mode of action (2). C. Name the group of pathogens to which NPV belongs (1) OR D. Justify why NPV use is a biocontrol method (1).

CBSE Class 12 Biology Marking Scheme 2027 (Solutions)

The 2026-27 marking scheme gives the correct option for every Section A question (including the visually-impaired versions) and value-point answers with the marks for each point in brackets for Sections B–E – e.g. ICSI and IVF-IUT with 1.5 marks each (Q22), the full Punnett square and 6:6:2:2 ratio (Q24), and tables of biodiversity threats or decomposition steps at 1 mark per row (Q33). Check your answers against it after you solve the paper.

Biology Marking Scheme 2027 – Read Online

CBSE Class 12 Sample Paper 2027 Solution (Marking Scheme) for Biology Open PDF

How to Score Well – Tips from the 2027 Paper

• Practise reading hypothetical data tables: Section B alone has three (Q19, Q20A, Q21) – state the trend in the data and give one biological reason, as the scheme gives 1 mark for each.
• Calculation-type MCQs appear: Meselson-Stahl generations after 60 minutes (Q7: 25% hybrid, 75% light) and 200 nucleosomes = 40,000 bp, 13,600 × 10^-9 m (Q10) – know 200 bp per nucleosome and 0.34 nm per bp.
• Genetics crosses carry step marks: in Q24 write parental genotypes and gametes, draw the full Punnett square, give the ratio (3:3:1:1) and scale it to 64 offspring (24) – each step is 1 mark.
• Molecular-biology long answers need codon work: Q31 asks you to identify point vs frameshift mutation in a DNA strand, translate it (Met + 6 Phe, 7 amino acids) and recognise degeneracy of the code.
• Learn NCERT terms precisely for one-word marks – cistron, baculovirus, insertional inactivation, parasitism/mutualism and the four decomposition steps (fragmentation, leaching, catabolism, humification/mineralisation).
• Solve the 2027 paper in one sitting with a timer, check it with the marking scheme, then solve the 2026 paper a few days later.

More Class 12 Biology Papers and Study Material

Practise past board papers, or plan your revision with the syllabus and important questions for Class 12 Biology:

CBSE Class 12 Biology Sample Paper 2027 – FAQs